The BioFluidica LiquidScan chip is a one-time-use test-specific microfluidic device. From 1 to 8 chips can be processed simultaneously on the LiquidScan system controlled to run autonomously by LiquidScan software. Circulating Tumor Cells (CTCs), for example, have a low abundance in blood, fetal cells, even less, against a high background of blood cells, RBCs 109 per ml; WBCs 107 per ml. Using antibody-surfaced channels, the microfluidic chip allows for the capture, isolation and enrichment of CTCs, fetal cells or exosomes. Elution of the cells and exosomes from the chip is performed such that the isolated material is fully compatible with downstream molecular and immunochemical analyses, as required for specific assays.